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Spotlight
Office of Public Health Genomics/CDC launches the CancerGEM KB
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CDC Office of Public Health Genomics in collaboration with NCI Division of Cancer Control and Population Sciences launches the CancerGEM KB: CancerGEM KB is an online resource for researchers, public health professionals, policy makers, and health care providers interested in the use of genomic information in cancer care and prevention. CancerGEM KB provides objective synthesis and timely dissemination of information on cancer human genome epidemiology (genetic associations, gene-environment interactions and gene prevalence information) and aggregated evidence on cancer genomic tests in transition to clinical and public health practice. CancerGEM KB also offers summary information on Genomic Tests through PLoS Currents Evidence on Genomic Tests, an open-access journal for systematic reviews and structured short summaries of evidence for the validity and utility of genetic tests.
Read more about CancerGEM KB
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News
related to genomic applications in cancer care and prevention
Potential Genomic Tests
recently added in
Cancer Genomic Test Finder
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04/30/2013
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Breast cancer, ovarian cancer
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BROCA cancer risk panel; next-generation sequencing (NGS); compete sequence of exons and flanking introns for 40 genes and detection of deletions, duplications, mosaicism; whole blood sample
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See detail
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04/01/2013
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Multiple conditions; 25 diseases and medical conditions
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DNA profile, analysis of single nucleotide polymorphisms (SNPs)
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See detail
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03/27/2013
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Prostate cancer
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gene expression profile
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See detail
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02/22/2013
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Diffuse large B-cell lymphoma (DLBCL)
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Algorithm combining two-gene expression signature (LMO2, CD137) and International Prognostic Index (IPI); reverse transcriptase-polymerase chain reaction (RT-PCR) assay; paraffin-embedded primary DLBCL tumor tissue sample
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See detail
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01/09/2013
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Cancer
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tumor genetic profile from next-generation sequencing (NGS) is compared against a panel of 45 cancer-related genes; blood sample and tumor sample (from surgery or biopsy)
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See detail
Published Literature
recently added in
Cancer HuGE Literature Finder
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3' untranslated region 1630 C>T polymorphism of prohibitin increases risk of breast cancer.
OncoTargets and therapy
2013
6
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Tang L, Zhao Y, Nie W, Wang Z, Guan X
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A comprehensive next generation sequencing based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma.
The Journal of clinical endocrinology and metabolism
2013
May
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Rattenberry E, Vialard L, Yeung A, Bair H, McKay K, Jafri M, Canham N, Cole TR, Denes J, Hodgson SV, Irving R, Izatt L, Korbonits M, Kumar AV, Lalloo F, Morrison PJ, Woodward ER, Macdonald F, Wallis Y, Maher ER
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A Novel Fully Automated Molecular Diagnostic System (AMDS) for Colorectal Cancer Mutation Detection.
PloS one
2013
8
(5):
5.
Kitano S, Myers J, Nakamura J, Yamane A, Yamashita M, Nakayama M, Tsukahara Y, Ushida H, Liu W, Ratain MJ, Amano M
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ABO Blood Group and Risk of Pancreatic Cancer: A Study in Shanghai and Meta-Analysis.
American journal of epidemiology
2013
May
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Risch HA, Lu L, Wang J, Zhang W, Ni Q, Gao YT, Yu H
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Association between GSTP1, GSTM1 and GSTT1 polymorphisms involved in xenobiotic metabolism and head and neck cancer development.
Molecular biology reports
2013
May
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Russo A, Francelin PR, Galbiatti AL, Raposo LS, Maníglia JV, Pavarino EC, Goloni-Bertollo EM
Published Evidence
recently added in
Cancer Evidence Aggregator
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CancerGEM KB (Cancer Genomic Evidence-based Medicine Knowledge Base) (version 1.0)
CancerGEM KB powered by HuGE Navigator infrastructure.